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Detecting Potential Toxicity in Mitochondria
Reported by: Dr. Venkat S. Karra, Ph.D. Mitochondria are responsible for more than 90% of a cell’s energy production via ATP (adenosine triphosphate) generation, in addition to playing a significant...
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Expanding the Genetic Alphabet and Linking the Genome to the Metabolome
Expanding the Genetic Alphabet and Linking the Genome to the Metabolome Reporter& Curator: Larry Bernstein, MD, FCAP Unlocking the diversity of genomic...
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Mitochondria: Origin from oxygen free environment, role in aerobic...
Reporter and Curator: Larry H Bernstein, MD, FACP Introduction Mitochondria are essential for life, and are critical for the generation of ATP. Otto Warburg won the Nobel Prize in 1918 for his...
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Is the Warburg Effect the Cause or the Effect of Cancer: A 21st Century View?
Is the Warburg Effect the Cause or the Effect of Cancer: A 21st Century View? Author: Larry H. Bernstein, MD, FCAP A Critical Review What is the Warburg effect? “Warburg Effect” describes the...
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What can we expect of tumor therapeutic response?
Author: Larry H. Bernstein, MD, FCAP, Writer, Author, Responder Clinical Pathologist, Biochemist, and Transfusion Physician...
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Directions for Genomics in Personalized Medicine
Directions for Genomics in Personalized Medicine Author: Larry H. Bernstein, MD, FCAP Purpose This discussion will identify the huge expansion of genomic technology in the search for...
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Targeting Mitochondrial-bound Hexokinase for Cancer Therapy
Author: Ziv Raviv, PhD Mitochondria are recognized as essential for both life and death fates of cells. Mitochondria are the site where oxidative phosphorylation happens, the process that is...
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Mitochondrial Metabolism and Cardiac Function
Mitochondrial Metabolism and Cardiac Function Curator: Larry H Bernstein, MD, FACP This article is the SECOND in a four-article Series covering the topic of the Roles of the Mitochondria in...
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Reversal of Cardiac Mitochondrial Dysfunction
Reversal of Cardiac mitochondrial dysfunction Curator: Larry H Bernstein, MD, FACP This article is the FOURTH in a four-article Series covering the topic of the Roles of the Mitochondria in...
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Mitochondrial Dysfunction and Cardiac Disorders
Mitochondrial Dysfunction and Cardiac Disorders Curator: Larry H Bernstein, MD, FACP This article is the THIRD in a four-article Series covering the topic of the Roles of the Mitochondria in...
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Disruption of Calcium Homeostasis: Cardiomyocytes and Vascular Smooth Muscle...
Disruption of Calcium Homeostasis: Cardiomyocytes and Vascular Smooth Muscle Cells: The Cardiac and Cardiovascular Calcium Signaling Mechanism Author, Introduction: Larry H Bernstein, MD, FCAP...
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A Synthesis of the Beauty and Complexity of How We View Cancer
A Synthesis of the Beauty and Complexity of How We View Cancer Author: Larry H. Bernstein, MD, FCAP Cancer Volume One – Summary A Synthesis of the Beauty and Complexity of How We View Cancer This...
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Introduction – The evolution of cancer therapy and cancer research: How we...
Larry H Bernstein, MD, FCAP, Author and Curator http://pharmaceuticalintelligence/4-2-2014/larryhbern/ Introduction (Cancer ebook 4)- The evolution of cancer therapy and cancer research: How we got...
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Studies of Respiration Lead to Acetyl CoA
Studies of Respiration Lead to Acetyl CoA Curator: Larry H. Bernstein, MD, FCAP In this series of discussions it has become clear that the studies of carbohydrate metabolism were highlighted by...
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The multi-step transfer of phosphate bond and hydrogen exchange energy
The multi-step transfer of phosphate bond and hydrogen exchange energy Curator: Larry H. Bernstein, MD, FCAP, Leaders in Pharmaceutical Intelligence In this subtext of the series we expand on a tie...
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Metabolomics, Metabonomics and Functional Nutrition: the next step in...
Metabolomics, Metabonomics and Functional Nutrition: the next step in nutritional metabolism and biotherapeutics Reviewer, Curator: Larry H. Bernstein, MD, FCAP The human genome is estimated to...
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Compilation of References in Leaders in Pharmaceutical Intelligence about...
Compilation of References in Leaders in Pharmaceutical Intelligence about proteomics, metabolomics, signaling pathways, and cell regulation Curator: Larry H. Bernstein, MD, FCAP Proteomics The Human...
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Metformin, thyroid-pituitary axis, diabetes mellitus, and metabolism
Metformin, thyroid-pituitary axis, diabetes mellitus, and metabolism Larry H, Bernstein, MD, FCAP, Author and Curator and Aviva Lev-Ari, PhD, RN...
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Isoenzymes in cell metabolic pathways
Larry H. Bernstein, MD, FCAP, Author and Curator Isozymes An example of an isozyme is glucokinase, a variant of hexokinase which is not inhibited by glucose 6-phosphate. Its different regulatory...
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Introduction to Metabolic Pathways
Introduction to Metabolic Pathways Author: Larry H. Bernstein, MD, FCAP Humans, mammals, plants and animals, and eukaryotes and prokaryotes all share a common denominator in their manner of...
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